Does Alli Work?

Kenny McCormick from South Park, Colorado
Model: Kenny McCormick from South Park, Colorado

Does Alli work?

Well, according to this editorial in the Lancet:


According to the big brains over at the Lancet:

  • The average weight loss with alli is only 2.5 kg / 5 lbs per year.
  • The cost of OTC alli is 6 times higher than the equivalent dose of prescription Orlistat.
  • Both OTC alli and prescription Orlistat have the unfortunate side effect of steatorrhoea

And, for those of you that don’t know what steatorrhoea is:

  • Steatorrhea is the presence of excess fat in feces.

As a result:

  • Stools may also float due to excess gas
  • Stools may have an oily appearance
  • Stools may be especially foul smelling
  • You may experience an increased number of bowel movements
  • You may experience an urgent need to have a bowel movement
  • You may experience an inability to control your bowel movements

And, as a result:

  • You may experience an oily anal leakage or some level of fecal incontinence.

And, just to remind you:

The average weight loss with alli is only 2.5 kg / 5 lbs per year.

Good Luck!


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The Lancet – doi:10.1016/S0140-6736(09)60115-X


  1. haha! But I don’t like that it’s just an ad for another diet pill. Still very funny, though! Anal leakage!!!

  2. As with any type of weight loss gimmick (from diet pills to fad diets to good old fashioned diet and exercise and everything in between) you’ll find people who love it, people who hate it, and people who are indifferent about it… But it’s usually good to hear from the people who didn’t like it because you’ll learn what could be bad, you hear what could be good from the commercials.

  3. The Alli marketing tries to spin the, uh, leakage issue by saying that this side effect helps a person learn for the future that they’ve made a food choice that’s too fatty- like shock aversion therapy, except you’ll have to make all new friends & burn your house when you’re finally skinny. It also doesn’t seem to discriminate between supposed good fats and bad- so fish, avacado, & nuts are out I guess, but i think Special K is low fat, so go tango. Fortified vitamins probably taste better than the ones in plants and such anyway, eh? Also worth nothing that their former sponser Wynona Judd didn’t have any success with it & has moved on to other, more successful albeit unconventional methods.

  4. Gastric band: didn’t work for many b/c they assumed they could go back and eat normally when they lost all the weight and took off the band despite being told otherwise, despite not being able to eat as much as they had before (so changing their eating pattern). They *knew* they couldn’t overat yet something else subconcious told them otherwise (their emotional response).

    So do I think Allie will work? no, for the exact same reason.

    The pill may work for some but not for all, just the same as the gastric band, just the same as liposcuction and even many diets.

    People need to deal with their own deep seated issues with food and learn it is a functional tool not something to party and pleasure themselves with (no that was not a pun! I meant that!!) people need to stop and take responsibility for their actions WHILST they are doing what they are doing. This is not impossible, its challenging but not impossible. If busy lives get in the way of eating more wisely then maybe those people need to accept defeat and cut back the business of their lives, share tasks. Governments and managers and companies also need to play a part eg in this respect stop expecting so much from people in the way of work so workers can gain some of their lives back, can watch their health, can have the mental energy for taking care of themselves.

    So many problems and Allie is not the way out because unhealthy weight gain is not the problem,
    because its only a symptom!

  5. it works i lost about 5 pounds but then i had to stop takeing it cuz the side effects are horribel i felt sick all the time like i had a tummy ace or something but the worst part was,ok it works by takeing all the fat out of the food you eat but it has to come out somewere right? so it comes out of your buttin like an oily fourm its so discusting and the more fat u eat the more oil comes out and its uncontrolabel i had to were a pad every day it was nasty!!

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