Previous research indicates that your SIRT1 proteins help keep you healthy & live longer by fixing errors in your DNA – cancer, UV light, free radicals, etc. With that being the case, it’s a good thing to have lots of healthy, active SIRT1 running all over your body fixing any DNA errors.
Our current methods of increasing SIRT1 activity include calorie restriction and the supplement Resveratrol.
In this most recent study, researchers put some test subjects through a HIIT workout consisting of 40 min (10 x 4 min intervals @ 90% peak oxygen consumption) of bike sprints interspersed with 2 min rest periods.
They found that:
- 4 days after training, there was a 28 to 36% increase in mitochondrial enzyme activity in your muscle.
- Total muscle SIRT1 activity increased by 31%
- Activity per SIRT1 protein increased by 58%, despite
- the quantity of SIRT1 decreasing by 20%
And what does all of that mean?
The increased mitochondrial enzyme activity results in improved aerobic & anaerobic endurance and reverses muscle atrophy caused by inactivity or natural aging. That’s good.
The increased SIRT1 means that damaged DNA is repaired before it can accumulate and cause genetic problems.
Because, if we believe that the DNA damage theory of aging is correct, when we prevent the accumulation of damaged DNA, we prolong our good health and extend our life span.
- HIIT increases SIRT1 activity
- SIRT1 activity prevents genetic errors
- Genetic errors are responsible for aging
- Aging is responsible for death (duh)
- Therefore, HIIT will help you live longer & better