What is MGmin LDL cholesterol?
- MGmin LDL is a version of LDL that has been modified by methylglyoxal (MG)
- MG is a potent arginine-directed glycating agent that is formed due to high blood sugar and related inflammation
- As a result, the plasma concentration of MG is increased 2x to 5x in patients with diabetes
But you’re not diabetic…so this doesn’t matter to you.
Or does it?
- According to this study, minimal modiﬁcation of LDL by MG decreases the particle size of pre-existing LDL cholesterol (similar to that of sdLDL) and….
- makes them stick together (increased aggregation) and….
- makes them stick to the walls of your arteries.
And that ain’t good.
Because if you take a whole bunch of small, dense LDL particles, bunch them together and then glue them to the inner wall of a coronary artery, you end up with:
- narrowed arteries
- reduced blood flow
- increased chance of rupture
- increased chance of blood clots
- increased chance of coronary heart disease (CHD)
- increased chance of heart attack and
- increased chance of death.
And that, most definitely, ain’t good.
So, where do we go from here?
- The researchers will continue researching in an attempt to discover treatments that could help neutralize MGmin LDLs harmful effects on patients’ arteries.
- You, however, are not a scientist. Your job is to cut back on the pizza & donuts and download my FREE Ebook – A Paleo Diet for the 21st Century.