What is MGmin LDL Cholesterol & why does it want to kill you?

What is MGmin LDL cholesterol?

  • MGmin LDL is a version of LDL that has been modified by methylglyoxal (MG)
  • MG is a potent arginine-directed glycating agent that is formed due to high blood sugar and related inflammation
  • As a result, the plasma concentration of MG is increased 2x to 5x in patients with diabetes

But you’re not diabetic…so this doesn’t matter to you.

Or does it?

  • According to this study, minimal modification of LDL by MG decreases the particle size of pre-existing LDL cholesterol (similar to that of sdLDL) and….
  • makes them stick together (increased aggregation) and….
  • makes them stick to the walls of your arteries.

And that ain’t good.

Because if you take a whole bunch of small, dense LDL particles, bunch them together and then glue them to the inner wall of a coronary artery, you end up with:

  • narrowed arteries
  • reduced blood flow
  • increased chance of rupture
  • increased chance of blood clots
  • increased chance of coronary heart disease (CHD)
  • increased chance of heart attack and
  • increased chance of death.

And that, most definitely, ain’t good.

So, where do we go from here?

  1. The researchers will continue researching in an attempt to discover treatments that could help neutralize MGmin LDLs harmful effects on patients’ arteries.
  2. You, however, are not a scientist. Your job is to cut back on the pizza & donuts and download my FREE Ebook – A Paleo Diet for the 21st Century.

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Reference

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0 comments

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